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Indeed, albuminuria and reduced kidney function have been addressed as partially responsible for the residual CV risk persisting despite correction of common CV risk factors 79

A theoretical multi-target strategy might combine: NAD+ for ongoing metabolic support: sirtuin activation, DNA repair, mitochondrial maintenance, nutrient sensing recalibration Epitalon for periodic telomere maintenance: cyclic telomerase activation to preserve replicative capacity and delay senescence onset This combination would address at least seven hallmarks between the two interventions