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ACTL6A impacts GSH de novo synthesis mainly by upregulating -glutamyl-cysteine synthesis To further assess the mechanism by which ACTL6A regulates GSH metabolism, we investigated the metabolic fate of U- 13 C glucose by liquid chromatography with mass spectrometry (LCMS), which produces -GC containing two 13 C atoms via GSH de novo synthesis pathway, GSH containing two 13 C atoms via GSH de novo synthesis or the SGOC pathway, or four 13 C atoms via both pathways (Fig

Afzaal M, Saeed F, Asghar A, Shah YA, Ikram A, Ateeq H et al (2022) Nutritional and therapeutic potential of soursop

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This review also summarizes and highlights current limitations in targeting the Th17/Treg balance for AR treatment and suggests future research directions, aiming to provide new insights and strategies for clinical management (Fig