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Temporally-regulated genetic access to IL-1beta-expressing cellular networks in homeostasis and following peripheral or central immune stimuli

Renal tubules are essential components of the kidney and are vulnerable to damage from factors such as hypoxia, toxins, metabolic disorders, and aging

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To correct for this, we performed RNA-seq analysis of hypothalami obtained from animals treated with daily injections of either GLP-1MK-801 or a dose of semaglutide that was equipotent in terms of weight-lowering efficacy over 5 days of treatment, that is, mice had achieved a comparable weight loss and reduction in food intake as that of GLP-1MK-801-treated mice (Extended Data Fig