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Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article

Swirl gently: Once diluent is added, swirl the vial gently until the powder is fully dissolved

Early work showed that Put, Spd, and Spm are enriched at synaptic terminals, but concluded that these polyamines are not themselves released as neurotransmitters (Seiler and Deckardt, 1976)