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Also, it contributes to mitochondrial activity by facilitating electron transfer, and playing a key role in ATP synthesis through its involvement in the electron transport chain (Mousavinejad et al., 2018)

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A convenience sample of children diagnosed with a precursor to hypermobile EDS at a tertiary hospital who were followed for three years found four factors that predicted disease severity and modestly predicted development of disability over time: multisystem involvement, pain, fatigue, and postural control

doi: 10.1371/journal.pbio.3001687 72 GriffithsPD