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Systemic organ involvement can occur in SJS/TEN through a variety of mechanisms

The typical daily dose ranges from 500 mg to 2,000 mg of curcuminoids (most of which is curcumin) from turmeric extracts , which may be as much as 95% curcuminoids

These can include: Headaches Nausea Dizziness Tingling or numbness in extremities Flushing If you encounter any of these side effects, it is crucial to get in touch with your healthcare practitioner

2What about NRF-2 and non-alcoholic fatty liver disease?2.1Cytosolic mechanism of NRF-2 Nuclear factor (erythroid-derived 2)-like 2 plays a transcendental role in the antioxidant and anti-inflammatory mechanism, it activates the elements of the antioxidant response (ARE) [9], all this related to Kelch-like ECH-associated protein nuclear factor (erythroid-derived 2)-like 2 (KEAP1-NRF2) [7,16]