l-carnitine 250 mg benefits | Linus Pauling Institute Willner Chemists | Pure Encapsulations

Second, mechanistic convergence in separate experiments is not the same as demonstrated synergy in a shared solution and a shared organism combining pro-angiogenic agents does not reliably multiply their effect, and uncontrolled angiogenesis is not an unambiguously good thing (the same vessel-forming signals that aid healing are, in other contexts, exactly what tumors exploit, which is why unsupervised pro-angiogenic stimulation is not casually assumed to be safe)

Butterfield et al

10.1007/BF00222722 200 RodierP

Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine