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For example, the inhibition of cell proliferation by curcumin has been associated with the Nrf2-dependent downregulation of DNA repair-specific flap endonuclease 1 (Fen1) in breast cancer cells in culture (46)

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Development of a humanized in vitro bloodbrain barrier model to screen for brain penetration of antiepileptic drugs

In some embodiments, administration of a formulation or composition or device described herein in conjunction with a cochlear implant or stem cell transplant has a trophic effect (e.g., promotes healthy growth of cells and/or healing of tissue in the area of an implant or transplant)