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Mieyal, Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases

Other related diseases such as fontal temporal dementia (FTD) appears to have overlap both with AD and ALS, and is commonly related with TDP-43 and C9ORF72 mutations of ALS (Warren et al., 2013), although there is evidence for TDP-43 involvement in AD, it appears to take a different progression pattern compared to ALS and FTD (Meneses et al., 2021), which suggests distinct disease mechanisms at play

Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines

Low BDNF levels are often observed in neurodegenerative diseases, depression, anxiety and cognitive problems