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Among them, -3 polyunsaturated fatty acids and polyphenols are important components of anti-inflammatory diets, while collagen peptides, vitamin D, calcium, probiotics, glucosamine, chondroitin and hyaluronic acid are commonly used in clinical practice as important nutritional support treatments or preventive measures for OA to promote cartilage repair

FIGURE 1 2 Materials and methods 2.1 Cell lines and cell culture L-02 hepatocytes from the Cell Bank of the Chinese Academy of Sciences (Shanghai, China) were cultured in Dulbeccos Modified Eagle Medium (DMEM) (Gibco, Grand Island, NY, United States) with 10% fetal bovine serum (FBS

riboflavin-5-phosphate) may affect its bioavailability and efficacy