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Intracellular ROS homeostasis is characterized by the ability of cells to adapt to changing conditions such as hypoxia, hyperoxia, and oxidative stress [4,5,6], while disruptions in this equilibrium can have significant implications for cell fate [7], disease progression [8], and therapeutic responses [9]

Glutathione plays a vital role in preserving brain health by increasing glutathione levels

this assigned the best hit for each of the ASVs and then provided the percentage of identical matches between the sequence of interest and the top hit as well as an e-value (i.e., the number of expected hits with a similar quality that could be found by chance)

The sATF6 protein then translocates to the nucleus and mediates apoptosis by promoting CHOP expression (Liang et al., 2020)