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In our study, neurons with dark eosinophilic cytoplasm and pyknotic nuclei were observed in the CA1 region of the hippocampus of KA-treated rats, and a decrease in the number of Purkinje cells in the gangliosum layer was observed in the cerebellum of KA-treated rats

The remaining single cells were normalized sample-wise to an equal sequencing depth of one million, and +1 was added to each genes count to allow for log 2 transformation

The results of cross-sectional studies of subclinical vascular disease show that higher homocysteine concentrations are associated with greater carotid artery intimal-medial wall thickness (Malinow et al, 1993