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Current research indicates that the cell cycle arrest depends on the activity of cyclin-dependent kinase inhibitors (CDK) p16 and p21, often regulated by the main tumor suppressor protein p53, whose elevated level is frequently used as a marker of senescence detection [21]

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Return-to-Sport or Activity Once symptoms improve, we guide you back to high-level function using reaction drills, return-to-lift programming, and task-specific progressions