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Targeting the multiple physiologic roles of VDAC with steroids and hydrophobic drugs

5.1 Intervention strategies 5.1.1 Targeting iron homeostasis Iron chelators such as deferoxamine, deferiprone, and deferasirox bind free ferrous iron (Fe2+), reducing substrate availability for the Fenton reaction and thereby curtailing the lipid peroxidation cascade (152)

Amla Enhances Mitochondrial Spare Respiratory Capacity by Increasing Mitochondrial Biogenesis and Antioxidant Systems in a Murine Skeletal Muscle Cell Line

The differences between various active peptides stem from their unique amino acid sequences and structures, which determine their specific interactions with biological pathways