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A novel and important finding from the present study is that dietary glycine supplementation upregulated GSH concentrations as well as the activities of enzymes for GSH formation in the tissues of HSB at two different stages of the life cycle (Table 1 and 2)

However, if these vasodilators enter the systemic circulation, they could contribute to ME/CFS symptoms such as fatigue, flu-like symptoms, pain, fever, and sleep disturbances, similar to the effects observed when vasodilators spill over in dysmenorrhea (346)