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The results showed that liraglutide had a modest positive effect on improving motor function and performed well in terms of safety and tolerability, although there were some manageable gastrointestinal side effects

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136 In addition, PPARs are involved in anti-inflammatory effects through a mechanism known as transrepression that inhibits nuclear factor-B (NF-B), activator protein-1 (AP-1), signal transducer and activator of transcription (STAT), or nuclear factor of activated T cells

The continued development of new PARP inhibitors with improved selectively and reduced side effects is critical for effective precision medicine in oncology