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In the 20th century, Goeckerman began to use high pressure mercury lamp combined with external application of coal tar to treat psoriasis and achieved good results, which was the beginning of modern phototherapy of UV radiation and also intriguingly presents a potential for its application in the treatment of cancer directly or indirectly [14]

Next, the Annexin V-FITC/PI double-staining assay revealed that ACE treatment induced cell death in HCT116 and RKO cells in a concentration-dependent manner, which was also confirmed by the calcein/PI double-staining assay (Supplementary Fig

Some individuals might experience benefits more quickly or slowly than others

Tamboli RA, Antoun J, Sidani RM, Clements A, Harmata EE, Marks-Shulman P, Gaylinn BD, Williams B, Clements RH, Albaugh VL, Abumrad NN