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The researchers used a powerful molecule called bone morphogenetic protein 2 (BMP2) to initiate bone formation after microfracture, but then stopped the process midway with a molecule that blocked another signaling molecule important in bone formation, called vascular endothelial growth factor (VEGF)

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In their study, they identified transporters for sugars, inorganic ions, amino acids and water, which indicated that the tegument plasma membrane was crucial for schistosomes to acquire nutrients from the host and help maintain solute levels

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