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For most individuals starting a combined protocol, basic ice packs or cold water immersion provides sufficient cryotherapy benefits without major investment

J Clin Endocrinol Metab (2001) 86(4):16728

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TBI induced alterations in cytokine profiles within brain tissue, with EA decreasing interleukin (IL)-6, IL-1, and tumor necrosis factor (TNF)- levels, while increasing IL-10 levels in the brain