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Furthermore, microbial metabolites, such as SCFAs, can be conveyed to the central nervous system via the vagus nerve, thereby affecting synaptic plasticity and neuroinflammation (Prata et al., 2017)

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Central obesity is associated with increased secretion of adipokines, which promote the release of pro-inflammatory mediators from peripheral tissues, elevating circulated androgen levels

We further investigated the molecular changes of NSBSO after GSH treatment by high-performance liquid chromatography (HPLC) analysis