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Both hyperuricemia and renal disposition of uric acid are polygenic traits and multiple haplotypes of renal urate transporters are increasingly recognized as significant factors

Zhang et al., 2021b) (Figure 4)

doi: 10.3748/wjg.v20.i31.10825 534 BaoBAliSBanerjeeSWangZLognaFAzmiASet al

Ferroportin (FPN), a divalent metal exporter, has been suggested as a possible candidate, as shown by its basolateral localization on the enterocytes ( Fpn KO mice (Seo and Wessling-Resnick, 2015)