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The induction of ferroptosis is tied to lipid peroxidation, amino acid metabolism, and iron metabolism, and has been linked to conditions including myocardial ischemia/reperfusion (MI/R), cardiac hypertrophy, cardiomyopathy, atherosclerosis, heart failure, and abdominal aortic aneurysm

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International Journal of Molecular Sciences (2022)

The evidence for this mechanism is less robust than the VEGF/angiogenesis or gut-lining signalling pathways, and it is typically characterised as a secondary or tertiary mechanism in BPC-157 research rather than a primary research focus