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Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

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Due to challenges in scaling the production of 9 different vaccine components, the group is currently developing quartet nanocages encoding RBDs from SHC014, Rs4081, RaTG13 and SARS-CoV-2 Wuhan-Hu-1 (Table 2)