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It has been demonstrated in a MC908 mouse model that coupling of LTC4 with its receptor CysLT2R, which is expressed in mice and in humans in a population of peripheral sensory neurons, represents a potent itch inducer [55, 56]

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Integrating our data with publicly available single nuclear RNA sequencing (snRNA-seq) showed enrichment of cognition-related genes in defined cell-types with established links to cognitive resilience, including SST interneurons and excitatory intratelencephalic cells