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Some doctors may even prescribe B12 injections to prevent deficiencies before they start (especially if your bloodwork's numbers are on the low side).If you suffer from anemia or a B12 deficiency, you may need B12 as a treatment

Saito J, Kohn AD, Roth RA, Noguchi Y, Tatsumo I, Hirai A, et al

Do not mix together with Vitamin C or retinol at the same application

Furthermore, decreased NAD+ levels, potentially a consequence of reduced kynurenine, may contribute to fatigue by impairing energy production, and disrupting the coordination of circadian rhythms necessary for effective sleep (reviewed in Dehhaghi et al., 2022)