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Gut virome sequencing in children with early islet autoimmunity

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NAPQI covalently binds to sulfhydryl groups in cellular proteins, especially mitochondrial proteins

The top 12 hub proteins encompassed diverse functional categories, including oxidative stress and metabolic activity (GAPDH), inflammation (CST3, TGFB1), and complement and coagulation pathways (C1QA, KNG1) (Fig