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This disparity is hypothesized to arise from differences in estrogen-mediated neuroprotection, lifestyle factors, and occupational exposure to neurotoxins (Ben-Shlomo et al., 2024) (Figure 2)

Yancey PH, Gerringer ME, Drazen JC, Rowden AA, Jamieson A

Glutathione disulfide sensitizes hepatocytes to TNF-mediated cytotoxicity via IKK- S -glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease