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Description

Beyond proteasomal targeting, non-canonical ubiquitin modifications, including K63-linked polyubiquitination, regulate signaling, endocytosis, kinase activity, and DNA damage responses, while mono- and multi-ubiquitination influence chromatin dynamics, DNA repair, and subcellular localization (Fig

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Single, double and triple knockout mutants for DHAR have been reported (Noshi et al

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Quick Tip: Before the first session, ask for a skin assessment

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