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In vivo oral administration of AESN notably elevated antioxidant levels, reduced peripheral corneal vascularization and minimized structural damage, including corneal epithelial loss and iridocorneal angle narrowing

Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study

Similarly, gene therapy offers the potential to modulate TH signaling pathways at the molecular and cellular level in specific cell types, such as by editing DIOs or TR genes, ensuring precise and localized therapeutic effects

For example, if a hospital were selected on CLABSI, CAUTI, and SSI, and failed validation, that hospital would receive the maximum Winsorized z -scores (that is, the worst score) for CLABSI, CAUTI, and SSI