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Built on a 4% crosslinked agarose matrix, it combines high flow rates, excellent mechanical strength, and low ligand leakage for consistent purification from lab to industrial scale

Animal handling and sample collection Rats' weights (gram) were recorded daily throughout the experiment for observing weight change

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de la Torre et al., Two main pathways are involved in MDMA metabolic clearance: (1) O-demethylenation partially regulated by CYP2D6 followed by catechol-O-methyltransferase (COMT)-catalyzed methylation (HMMA) and/or glucuronide/sulfate conjugation