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Figure 2 4.3.2 Amplification of immune responses by released intracellular components following ferroptosis When ferroptosis leads to the rupture of chondrocytes or synovial cells, the oxidized lipid byproducts, iron ions, and damage-associated molecular patterns (DAMPs) that leak from these cells are detected by nearby immune cells

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One analysis did report a reduced risk of melanoma, but this was a cancer-specific finding rather than evidence that high-dose B vitamins prevent cancer generally

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement