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As it relates to disease development, Liu and Guo (2012) reported aberrant expression of DNMTs in eutopic endometrium of patients with adenomyosis

In contrast, GSTP1 promotes ER stress-induced apoptosis in liver cancer by glutathionylating SERCA, thereby inhibiting pro-survival MAPK8 signaling 50

Tretinoin is supported by multiple large, well-controlled clinical trials dating back to the late 1980s

HP 13 C MR via dissolution dynamic nuclear polarization (dDNP) is an emerging imaging technology that allows direct visualization of metabolic conversion of 13 C-enriched molecules, and has been applied extensively to study metabolism in cells, tissues, animal models, and patients 22,23,24