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Firstly, although we observed that the frequency and magnitude of Ca 2+ oscillation were more pronounced in cells from GCGR-KO mice, the detailed mechanism still needs to be elucidated
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2022 Aug;54:102392
At that time, we believed that the July 1 deadline would provide an appropriate balance between the necessity for adequate time to fully evaluate the applications, the requirement to publish the IPPS final rule by August 1 of each year, and addressing commenters' concerns that potential new technology applicants have some flexibility with respect to when their technology receives FDA approval or clearance
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