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This research was financially supported in part by grants from the National Natural Science Foundation of China (31370332), Plan for Scientific Innovation Talent of Henan Province (144200510017), National Key Research and Development Program (2016YFD0101006) and the Ministry of Agriculture of China (2016ZX08009-003)

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69,70 Small nerve fibers may become sensitized following increased distal terminal injury and regeneration in the presence of neurotrophins