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An important part of this is that FOXO4 lives in the nucleus of the cell and p53 does its work at the mitochondria two different parts of the cell

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PGC-1alpha activity in nigral dopamine neurons determines vulnerability to alpha-synuclein

In this study, the ability of MSCs to improve EAE model by re-myelination and to reduce inflammation was associated with HGF secretion and MET activation