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When you combine them, you could theoretically have the best of both worlds

Multiple clinical trials and controlled studies have demonstrated: Statistically significant improvements in skin firmness and elasticity with consistent use Reduction in fine lines and wrinkle depth over 3-6 months of application Improved skin density, moisture retention, and surface texture Reduction in photodamage and hyperpigmentation Tightening of loose skin documented in both topical and injectable applications Citation: Leyden JJ et al

Are there supplements I should avoid, or be taking, due to this drug

Higher dosage naturally increases the per-session price