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Compound concentration in the donor and acceptor wells were calculated from calibration curves spanning 400 3.125 M

Weight loss plateau lasting more than 4 weeks A plateau of 2 to 3 weeks is normal and does not require dose changes

Tirzepatide gives people a window of reduced appetite during which they can establish healthier eating patterns, develop exercise habits, and restructure their relationship with food

By 104 weeks, approximately 77% of SELECT patients on dose were receiving the target semaglutide 2.4 mg weekly dose, which is lower than the corresponding proportion of patients in STEP 1 (89.6% were receiving the target dose at week 68) 14,21