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3.2 Hepatic Impairment Study A total of 57 participants were screened and 32 were exposed to cagrilintide (full analysis set and safety analysis set: normal hepatic function, n = 14

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Upregulated GH receptor mRNA and protein in tendon fibroblasts Effect was dose-dependent and observed within 24 hours Provides a mechanistic link between BPC 157 and tissue growth/repair BPC 157 and blood vessels2019Vascular Review of BPC 157s vascular effects: promotes angiogenesis, protects endothelium, and counteracts vascular disruption in multiple injury models including thrombosis and ischemia-reperfusion