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Spontaneous activity tests A mouse was placed in a clear glass cylinder and recorded with a video camera for 3 min in a quiet area, to prevent distractions and accidentally causing freezing behaviour

Song Z, Revelo X, Shao W, Tian L, Zeng K, Lei H, et al

Under oxidation conditions, TRPV1 can overexpress tumor necrosis factor receptor 1 (TNFR1) in DRG cells through a ROS-mediated signaling pathway, which could bind with proinflammatory cytokine tumor necrosis factor (TNF-) to increase inflammatory conditions and nociception (Westlund et al., 2010)