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Fluoxetine also decreased the activity of 17-beta-hydroxysteroid dehydrogenase type 6 (17-HSD6), a steroidogenesis-related enzyme, and lowered serum testosterone levels by affecting the steroidogenic capacity of Leydig cells

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Beads were washed once with 700 L of 0.05% NP-40 and 1x protease inhibitor cocktail in IP, once with 700 L of 0.05% NP-40 in IP, and 3 times with 700 L of IP

In addition to synthesis of hormones the kidneys also function in the regulation of the production of other hormones such as calcitriol (1,25-dihydroxyvitamin D 3 ) and angiotensin II