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Data from designated brain regions from the cFOS 3D brain imaging study were analysed using one-way ANOVA with Dunnets post hoc multiple-comparison test relative to the vehicle, using a negative binomial generalized linear model to control for Gaussian distribution

Among its isoforms, NOX2 is predominantly expressed in Kupffer cells and is activated via toll-like receptor 4 (TLR4) signaling, resulting in superoxide production and pro-inflammatory cytokine release [113, 114]

Review literature discussing these models frequently highlights the interaction between BPC-157 and nitric oxiderelated signaling systems involved in epithelial-endothelial communication and mucosal barrier maintenance [2]

Used alongside BPC-157, it addresses different layers of the same problem: BPC-157 targets the mucosal barrier and cytokine signalling