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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)

Keywords: antimicrobial peptides, anticancer mechanisms, drug combination, anticancer application, peptide nano agents Graphical Abstract Introduction Cancer, as one of the most lethal diseases in the world, is still a serious threat to human survival