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It's been a few months and my skin looks smoother, fresher, and more radiant than it ever has

Less common systemic effects include mild lightheadedness (possibly copper-related), temporary headache, and occasional mild fatigue

Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age

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