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Using a rat model of hind limb suspension (HLS) for 10 days, we induced marked muscle atrophy that was accompanied by enhanced muscle proteolysis and reduced muscle protein content
Notably, PAX4 and NKX2-2 enhanced the yield of -like cells compared to PNM treatment alone ( Transdifferentiation into -cells is possible from -, -, acinar, ductal, intestinal EECs, and even fibroblasts, via regulation of key transcription factors including PNM, PAX4, and Arx/Dnmt1
Fathizadeh H, Milajerdi A, Reiner , Kolahdooz F, Chamani M, Amirani E et al (2019) The effects of l-carnitine supplementation on serum lipids: a systematic review and meta-analysis of randomized controlled trials
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