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Therefore, the clearance of senescent cells through apoptosis is one of the proposed mechanisms to reduce the burden imposed by the presence of senescent cells and in consequence, prevent age-related diseases and ultimately revert aging 3

The most 3 TSS gives rise to the shorter, major message (GSTF8-S) that is much more stress-responsive than the longer transcript (GSTF8-L) originating from an upstream TSS, which encodes the larger form of the protein

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