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This enzymatic reaction consumes both nicotinamide and SAM, leading to depletion of NAD+ storesa critical coenzyme required for cellular energy production, DNA repair, and metabolic regulation

If left untreated, it can lead to Heart palpitations and shortness of breath Weakness, tiredness, or lightheadedness Pale skin Vision loss Constipation, diarrhea, loss of appetite, or gas A smooth tongue Depression Memory loss Behavioral changes Numbness or tingling Muscle weakness Problems walking not trying to give you the wobbles here!), low levels of B12 can be linked to the development of pernicious anemia, dementia, or osteoporosis

Molecular targeted therapy for anticancer treatment