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This review synthesizes current evidence linking microbiota alterations to Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and strokeincluding post-stroke cognitive impairment (PSCI), as well as major depressive disorder (MDD), bipolar disorder (BD), anxiety disorders, post-traumatic stress disorder (PTSD), and chronic fatigue syndrome (CFS)

Although homocysteine thiolactone has not been unequivocally identified in vivo , it might be a major by-product of deregulated homocysteine metabolism

doi: 10.1016/j.animal.2024.101127 107 ReikW.DeanW.WalterJ

Headaches or Flu-like Symptoms Some individuals report mild, flu-like symptoms or headaches following treatment with neuromodulators