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Antiinfect Agents

Gene regulation by ECDs of IR and IGF1R To determine the contribution of the extracellular versus intracellular domains of the insulin and IGF-1 receptors in gene regulation, the data were further analysed by grouping cells expressing receptors with the IR-ECD (IR and IR/IGF1R) versus cells expressing receptors with IGF1R-ECD (IGF1R and IGF1R/IR) (Fig