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250 The second RCT reported in a much larger sample (131 BCG patients, 134 placebo patients) no differences in response rate between treatment arms (21% in the BCG group compared to 12% in the placebo groups) at seven months with 95% of patients in each group reporting at least one AE

Sepsis is a systemic inflammatory response caused by excessive cytokine secretion, such as interleukin (IL)-6, IL-10, IL1 and TNF-

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