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Cellular autophagy not only plays an important role in kidney development and maintenance of homeostasis of podocytes, endothelial cells, and tubular epithelial cells but also has been implicated in the pathogenesis of several renal diseases

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Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders

Using the selection of UPR-regulated mRNAs in Figure 1A as a broad indicator of ER stress signaling, we found that etomoxir also diminished UPR activation in C2C12 myoblasts (Figure 1D), and immortalized (data not shown) and primary (Figure 1E) brown adipocytes